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Puerarin Extract
2023-12-09 18:20  Visit:170
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1.What is Puerarin?

 

Puerarin Extract is also known as Puerarin. It is an isoflavone derivative with a crown-expanding effect isolated from the traditional Chinese medicine Pueraria lobata. Derived from the roots of Pueraria lobata (Willd) Ohwi and Pueraria thunbergiana Benth. The main chemical components are flavonoids Pueraria flavonoids, brown powder with low content, white needle-like crystal powder with high content, mp 187℃. Dissolved in methanol, slightly soluble in ethanol, slightly soluble in water, insoluble in chloroform or ether.
It has the effects of improving immunity, enhancing myocardial contractility, protecting myocardial cells, lowering blood pressure, and anti-platelet aggregation. It is widely used in the field of medicine.

 

Puerarin is an isoflavone that exists in a variety of plants, including some medicinal plants, especially the rhizomes of Pueraria plants, such as the traditional Chinese medicine Puerarin, and Pueraria lobata. Puerarin is an 8-C-glucoside of daidzein.
Clinically, it is used for coronary heart disease, angina pectoris, and hypertension.

 

Pueraria lobata

 

Pueraria Mirifica

Chinese herbal material Pueraria lobata

 Puerarin

 

 

 

 

2. Chemical & Physical Properties

 

CAS Number

3681-99-0

Molecular Weight

432.378

Density

1.6±0.1 g/cm3

Boiling Point

791.2±60.0 °C at 760 mmHg

Molecular Formula

C21H20O9

Melting Point

187-189°C

Common name

Puerarin

Flash Point

281.5±26.4 °C

 

 

3. Product quality specification & standard

 

Product name

Puerarin

Extract source

It is the dry root of the leguminous plant Pueraria lobata

Extraction Solvent

Ethyl alcohol

Appearance

White powder

Solubility

Dissolved in methanol, slightly soluble in ethanol, slightly soluble in water, insoluble in chloroform or ether.

Identification

TLC, HPLC

Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay of 98% Puerarin (HPLC test, percent, Standard in House)

Min. 95.0%

Residual Solvents

 

- N-hexane

NMT 290 PPM

- Methanol

NMT 3000 PPM

- Acetone

NMT 5000 PPM

- Ethyl Acetate

NMT 5000 PPM

- Ethanol

NMT 5000 PPM

Pesticide Residues

 

- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT)

NMT 0.05 PPM

- Aldrin, Endrin, Dieldrin

NMT 0.01 PPM

Microbiological Quality (Total viable aerobic count)

 

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Storage

In a Tight, Light-resistant, and Dry Place. Avoid Direct Sunshine. 

Shelf life

24 months

 

 

22Application

It is mainly used for the treatment of alcoholism, retinal artery and vein occlusion, sudden deafness, myocardial infarction, Coronary heart disease, angina pectoris, hypertension, hyperlipidemia, and other diseases.

 

 

5. Pharmacological effect

 

a. Contains saponins, which have a protective effect on liver tissue immune damage.

b. Can effectively reverse chemically induced liver fibrosis.

c. Enhance myocardial contractility and protect myocardial cells.

d. It can dilate blood vessels, lower blood pressure and improve microcirculation.

e. Protect the deformability of red blood cells and enhance the function of the hematopoietic system.

f. Anti-platelet aggregation, increases fibrinolytic activity and reduces blood viscosity.

g. It has a protective effect on nephritis and renal failure models.

h. It has an obvious regulatory effect on non-specific immunity, humoral immunity, and cellular immunity.

i. It can promote the transformation rate of lymphocytes in normal people and tumor patients, and enhance the effect of natural hormones.

j. It has an obvious stimulating and inducing effect on the interference system.

 

 

 7. Kintai manufacturing base

 

 

 

8. Kintai R&D center

 

 

 

★If you want to get high-quality Puerarin Extract, please feel free to contact us at  or feedback on the next page.

 

http://www.kintai-bio.com/

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